Peptide hormones play crucial roles in regulating various physiological processes. Let’s explore some notable peptide hormones,
CJC-1295, Thyrotropin-Releasing Hormone, Glucagon, Calcitonin, Vasopressin & Hepcidin Proteins
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Best describe as Growth hormone (GH) or simply human growth hormone (HGH) are known as somatotropin which help stimulate cell growth and reproduction, which leads to increased cell regeneration in human bodies. Some Researchers hold that GH is essential in regular human development and vice versa. While
as a peptide hormone, its mitogen that is specifically present in certain types of cells.
Among the many forms of human growth hormone found in the medicinal and pharmaceutical worlds. The most common is the recombinant form that’s given as a prescription drug to children with growth problems and deficiency. HGH has also been banned by many major sports and athletics committees due to the role it plays in the human body. It can be used as an anabolic steroid to elicit performance advantages in athletes.
Growth Factors
Growth hormone Function
Knowing that Growth hormones mainly has anabolic effects to regulate fat
and muscle on tissues. Which means it tends to help build ups.
Common example of its function is children with low growth spurts -
are known to have a deficiency in human growth hormone.
But, the function of HGH doesn’t end here. It is also known to help improve calcium retention in cells, which leads to an increase in bone strength. Furthermore, it can help improve and increase muscle mass through a process known as hypertrophy. In conjunction with this. HGH also boosts protein synthesis in the body.
Human growth hormone also acts to grow all the organs in the body, with the exception of the brain. It also reduces the way the liver takes in glucose, and can play a key role in homeostasis. Another well-known function of this growth hormone is the way it acts to stimulate the immune system.
Mechanism/Interactions
HGH stimulates height in children by at least two different mechanisms. The first is that GH uses some of its effects to connect with receptors on target cells, activating something known as the MAPK/ERK pathway. By doing this, growth hormone can help divide and multiple chondrocytes of cartilage. This is important because most polypeptide hormones can’t penetrate cell membranes due to them not being fat-soluble. Secondly, growth hormone helps to induce the production of IGF-1 (insulin-like growth factor 1). It does this through the JAK-STAT signaling pathway. It interacts with the liver, which is the main place where IGF-1 is produced. IGF-1 is known to help stimulate growth in many different tissues.
Structure
Human growth hormone is primarily comprised of a protein weighing 22, 124 daltons. It contains 191 amino acids, and the structure can be described as having four helices. These helices are essential for interacting with the GH receptor, which helps elicit its various functions. A closer look at the structure of GH reveals that it is homologous to prolactin and chorionic somatomammotropin.
There are many growth hormones present in different species, but only human growth hormone and old world monkey growth hormone will have any effect on the HGH receptor.
Thyrotropin-Releasing Hormone
CJC-1295
$396.00
A synthetic peptide derivative of GHRH
$433.00
Guanylin
(trifluoroacetate salt)
Corticosterone
Calcitonin
A peptide hormone that lowers blood calcium levels
$139.00
Gonadorelin (acetate)
Formal Name
: luteinizing hormone-releasing factor (swine), acetate.
CAS Number: 52699-48-6
A tropic hormone
$565.00
$904.00
ACTH stimulation test
ACTH (4-11)
Adrenocorticotropic hormone
MF
Formula Weight
: 1260.378
Purity: ≥98%
Formulation:Crystalline solid
Solubility:
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 0.25 mg/ml
PBS (pH 7.2): 10 mg/ml
Peptide Hormone
Glucagon (hydrochloride)
A peptide hormone
Formal Name
: glucagon (swine), hydrochloride.
CAS Number: 19179-82-9
MF
Formula Weight
: 3482.8
Purity: ≥95%
Formulation: A solid
Solubility:
Formic Acid: 10 mg/ml
Synonyms
: Adrenocorticotropic Hormone (1-39)
MF
Formula Weight
: 4541.1
Purity: ≥95%
Form: A lyophilized powder
Solubility:
Formic Acid: 1 mg/ml
$315.00
Peptide Hormone
Formal Name
: α1-24-corticotropin, acetate
CAS Number: 60189-34-6
Synonyms: ACTH (1-24)
Adrenocorticotropic Hormone 1-24, Tetracosactide
Formula Weight
: 2993.5
Purity: ≥95%
Form: A crystalline solid
Solubility:
MF
PBS (pH 7.2): 10 mg/ml
Formal Name
: L-prolylglycyl-L-threonyl-L-cysteinyl-L-α-glutamyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine, cyclic (4→12),(7→15)-bis(disulfide), trifluoroacetate salt.
MF
Formula Weight
: 1458.7
Purity: ≥98%
Formulation: A solid
Solubility :Water: 1 mg/ml
A peptide hormone activator of GC-C
Formal Name:
L-tyrosyl-D-alanyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide
CAS Number
: 446036-97-1
Syns
: Modified GRF (1-29)
CJC-1295-no DAC
GHRH (1-29)-NH2
MF
Formula Weight
: 3367.9
ACTH (18-39) (human)
A peptide fragment of ACTH
CAS Number:
53917-42-3
Synonyms
: Adrenocorticotropic Hormone (18-39)
Corticotropin-like Intermediate Lobe Peptide
RPVKVYPNGAEDESAEAFPLEF
MF
Formula Weight
: 2465.7
Purity: ≥95%
Formulation: A solid
Solubility:
DMF: 2.5mg/mL
DMSO: 5mg/mL
PBS (pH 7.2): 5mg/mL
$401.00
A tropic hormone
Formal Name:
5-oxo-L-prolyl-L-histidyl-L-prolinamide
CAS Number: 24305-27-9
Syns: Thyroliberin
TRF, TRH
TSH-releasing Hormone
MF
Formula Weight
: 362.4
Purity: ≥98%
Formulation: crystalline solid
Solubility:
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 30 mg/ml
PBS (pH 7.2): 10 mg/ml
$515.00
Formal Name
:11β,21-dihydroxy-pregn-4-ene-3,20-dione.
CAS Number: 50-22-6
Syns: 17-deoxy Cortisol
11β,21-DHP
NSC 9705
11β,21-dihydroxy
Progesterone
A steroid hormone used as a stress biomarker
MF
Formula Weight
:346.5
Purity: ≥98%
Form: A crystalline solid
Solubility:
$184.00
DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 25 mg/ml
Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
A peptide fragment of ACTH
Formal Name
:L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysine.
CAS Number: 67224-41-3
Syns: MEHFRWGK-OH
MF
Formula Weight
:1090.3
Purity: ≥98%
Form: A solid
Solubility:
DMF: 10mg/mL
DMSO: 10mg/mL
PBS (pH 7.2): 10mg/mL
$250.00
D-Aspartic Acid
An amino acid and a precursor in NMDA biosynthesis
CAS Number:
1783-96-6
Syns: NSC 97922
MF
Formula Weight
:133.1
Purity: ≥95%
Form: A crystalline solid
Solubility: PBS (pH 7.2): 10
mg/ml
$153.00
Syns:
Ba 47175
Calcitonin (1-32)
hCT
Thyrocalcitonin
MF
Formula Weight
:3417.9
Purity: ≥95%
Form: A lyophilized powder
Solubility: Water: 1 mg/ml
$384.00
ACTH (1-13)
A peptide fragment of ACTH
Formal Name
:α1-13-corticotropin, trifluoroacetate salt.
Syn: SYSMEHFRWGKPV-OH
MF:
Formula Weight
:1623.8
Purity: ≥98%
Form: A solid
Solubility:
DMF: .2mg/mL
DMSO: 10mg/mL
Ethanol: slightly soluble
PBS (pH 7.2): 10mg/mL
$234.00
Corticostatin (Defensins)
A corticostatic peptide
Syns:
DEFA4 Protein
α-Defensin 4
Defensin HNP-4
H. Neutrophil Peptide 4
Neutrophil Defensin 4
MF
Formula Weight
:3709.4
Purity: ≥95%
Form: A lyophilized powder
Solubility: Water: 1 mg/ml
$582.00
Neuropeptide S
A neuropeptide NSPR agonist
Syns: NPS
MF
Formula Weight
:2187.5
Purity: ≥95%
Form: A lyophilized powder
Solubility: Water: 1 mg/ml
$193.00
α-Helical CRF (9-41) (trifluoroacetate salt)
A synthetic peptide CRF antagonist
MF
Formula Weight
:3826.4
Purity: ≥95%
Form: A solid
Solubility: DMF: 30 mg/mL
DMSO: 30 mg/mL
Ethanol: 30 mg/mL
$482.00
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Top Purity Peptide Hormones